Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987052 | 1.00 | KMT2A (0.38) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19987026 | 0.93 | KMT2A (0.38) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL29979968 | 0.93 | KMT2A (0.38) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19987075 | 0.91 | KMT2A (0.39) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19784124 | 0.90 | KMT2A (0.32) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19987061 | 0.84 | EPHA2 (0.46) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL29979688 | 0.83 | KMT2A (0.39) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19986891 | 0.83 | KMT2A (0.39) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19784135 | 0.83 | KMT2A (0.33) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL19973794 | 0.81 | EPHA2 (0.35) | KMT2ALMNACYP2C9ATP6V1B2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689656-B | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-10-04 | — | — | CN | disclosed |