Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31145067 | 1.00 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL31145171 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL24364537 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL24366170 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL24365829 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL25321084 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL19214142 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL24365678 | 0.77 | MEN1 (0.49) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL24364035 | 0.76 | PIK3C3 (0.34) | — | |
| SCHEMBL25336001 | 0.76 | MEN1 (0.40) | MEN1KMT2AMAPK1PKMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
| US-11492350-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | SLC6A2 885/4885SLC6A4 1165/4885SLC6A3 526/4885 |
| US-11492350-B2 | Compounds and methods of use | F12, C1R, ABCG2 | SLC6A2 885/4885SLC6A4 1165/4885SLC6A3 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.