Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 11/20 | 0.68 |
| ▸ | IGF1R | P08069 | 6/20 | 0.55 |
| ▸ | MET | P08581 | 6/20 | 0.55 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674958 | 1.00 | CFTR (0.68) | CFTRIGF1RMETSRCMAOB | |
| SCHEMBL29981450 | 0.89 | IGF1R (0.71) | CFTRIGF1RMETSRC | |
| SCHEMBL28654859 | 0.89 | IGF1R (0.71) | CFTRIGF1RMETSRC | |
| SCHEMBL29981145 | 0.86 | IGF1R (0.73) | CFTRIGF1RMETSRC | |
| SCHEMBL28648880 | 0.86 | IGF1R (0.73) | CFTRIGF1RMETSRC | |
| SCHEMBL17144814 | 0.81 | CFTR (0.70) | CFTRMAOB | |
| SCHEMBL12707173 | 0.81 | CFTR (0.61) | CFTR | |
| SCHEMBL396336 | 0.81 | CFTR (0.66) | CFTRMAOB | |
| SCHEMBL398391 | 0.81 | CFTR (1.00) | CFTRMAOB | |
| SCHEMBL24254359 | 0.80 | CFTR (0.68) | CFTRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461612-B | Quinolone tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |