Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009942 | 0.85 | S1PR1 (1.00) | S1PR1KMT2A | |
| SCHEMBL3010430 | 0.84 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL3005146 | 0.84 | S1PR1 (1.00) | S1PR1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL3013815 | 0.80 | S1PR1 (1.00) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL2381271 | 0.79 | S1PR1 (0.65) | S1PR1 | |
| SCHEMBL12248510 | 0.78 | S1PR1 (0.64) | S1PR1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL12249607 | 0.75 | S1PR1 (0.60) | S1PR1KMT2A | |
| SCHEMBL12249525 | 0.74 | S1PR1 (0.59) | S1PR1KMT2A | |
| SCHEMBL12249460 | 0.74 | S1PR1 (0.59) | S1PR1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL12249426 | 0.74 | S1PR1 (0.62) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197749-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB | 2010-08-05 | — | — | US | disclosed |
| US-20100197749-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB | 2010-08-05 | — | — | US | disclosed |
| US-20100197749-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB | 2010-08-05 | — | — | US | disclosed |
| EP-1979332-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007083089-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007083089-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197749-A1 | CHEMICAL COMPOUNDS | EDF1, ECE1, EDNRA | S1PR1 945/4885KMT2A 2713/4885CYP2D6 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.