Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.71 |
| ▸ | GSK3A | P49840 | 5/20 | 0.71 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5408153 | 0.91 | STK17A (0.61) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL29985551 | 0.87 | GSK3B (0.69) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1918620 | 0.85 | STK17A (0.59) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1916449 | 0.85 | GSK3B (0.67) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1916451 | 0.85 | GSK3B (0.67) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1918619 | 0.85 | GSK3B (0.67) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1916270 | 0.83 | GSK3B (0.56) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL3282380 | 0.83 | GSK3B (0.56) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1916273 | 0.83 | GSK3B (0.56) | GSK3BGSK3ASTK17AMAPTMEN1 | |
| SCHEMBL1916209 | 0.83 | STK17A (0.53) | GSK3BGSK3ASTK17AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206730-A1 | PYRIMIDOPYRAZINE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-06 | — | — | WO | disclosed |