Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29984748 | 0.88 | USP2 (0.42) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL18418334 | 0.85 | USP2 (0.47) | USP2SMN1; SMN2RECQLHPGDEPHX2 | |
| SCHEMBL21193117 | 0.85 | USP2 (0.44) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL1489016 | 0.80 | USP2 (0.50) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL1247009 | 0.79 | USP2 (0.51) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL31401252 | 0.79 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| Hydrochloric Acid SCHEMBL22776359 | 0.78 | USP2 (0.50) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL12654039 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL21886745 | 0.77 | NR1H2 (0.39) | USP2SMN1; SMN2NR1H2RECQLDDB1 | |
| SCHEMBL421751 | 0.75 | USP2 (0.44) | USP2SMN1; SMN2NR1H2RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561952-A | RAS inhibitors | 锐新医药公司 | 2024-08-30 | — | — | CN | disclosed |
| EP-4346898-A1 | METHODS FOR INHIBITING RAS | Revolution Medicines, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-4334321-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022251292-A1 | METHODS FOR INHIBITING RAS | Revolution Medicines, Inc. (US) | 2022-12-01 | — | — | WO | disclosed |
| WO-2022235864-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2022-11-10 | — | — | WO | disclosed |