Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CSF1R | P07333 | 3/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 1/20 | 0.66 |
| ▸ | FRK | P42685 | 1/20 | 0.66 |
| ▸ | CLK2 | P49760 | 1/20 | 0.66 |
| ▸ | GSK3A | P49840 | 1/20 | 0.66 |
| ▸ | GSK3B | P49841 | 1/20 | 0.66 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.66 |
| ▸ | STK3 | Q13188 | 1/20 | 0.66 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.66 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.66 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111563 | 0.85 | PIM1 (1.00) | PIM1MAPTCSF1RKDM4EGAA | |
| SCHEMBL12955777 | 0.84 | PIM1 (0.59) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL12630093 | 0.84 | PIM1 (0.59) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL8923670 | 0.82 | KDM4E (0.55) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL4851140 | 0.81 | CSF1R (0.76) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL4847744 | 0.80 | MAP2 (0.72) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL24095581 | 0.80 | KDM4E (0.79) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL9363357 | 0.80 | CSF1R (1.00) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| SCHEMBL8784678 | 0.79 | PIM1 (0.51) | PIM1MAPTCSF1RROCK2MAP4K4 | |
| Hydrochloric Acid SCHEMBL4854389 | 0.79 | MAP2 (0.71) | PIM1MAPTCSF1RROCK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220323494-A1 | Novel Control Switch | GLAXOSMITHKLINE IP DEV LTD (GB) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220323494-A1 | Novel Control Switch | TNFRSF9, TNFRSF1A, TNFSF11 | PIM1 469/4885MAPT 1826/4885CSF1R 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.