⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16611387 | 0.85 | — | — | |
| SCHEMBL29197949 | 0.64 | — | — | |
| SCHEMBL27040926 | 0.61 | — | — | |
| SCHEMBL16612067 | 0.60 | — | — | |
| SCHEMBL519522 | 0.59 | — | — | |
| SCHEMBL13471186 | 0.59 | — | — | |
| SCHEMBL2262060 | 0.59 | — | — | |
| SCHEMBL17773099 | 0.58 | — | — | |
| SCHEMBL3695688 | 0.57 | — | — | |
| SCHEMBL6207167 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-11117896-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20200048253-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-10556905-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-11 | — | — | US | disclosed |
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |
| CN-109312041-A | The solidification composition filling with high impact and heat resistance based on epoxy resin and polyisocyanates | 汉高股份有限及两合公司 | 2019-02-05 | — | — | CN | disclosed |
| US-20180258089-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-09-13 | — | — | US | disclosed |
| US-10023573-B2 | Beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-7786310-B2 | Acetic acid (2-benzyl-3-(2-hydroxy-ethyl)-3-isobutyl-isoxazolidin-5- ylmethylene)-hydrazide; fused to a DNA binding domain to repress or activate gene expression; libraries; gene therapy | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-08-31 | — | — | US | disclosed |
| US-20070105151-A1 | Small molecule transcriptional activation domains | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-05-10 | — | — | US | disclosed |
| EP-0564972-B1 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AG (DE) | 1999-08-11 | — | — | EP | disclosed |
| EP-0455133-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0413277-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| EP-0370453-B1 | Peptides having a Brady kinine-inhibiting activity | HOECHST AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0564972-A2 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0370453-A2 | Peptides having a Brady kinine-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |