Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 18/20 | 0.50 |
| ▸ | EED | O75530 | 17/20 | 0.50 |
| ▸ | RBBP4 | Q09028 | 17/20 | 0.50 |
| ▸ | SUZ12 | Q15022 | 17/20 | 0.50 |
| ▸ | AEBP2 | Q6ZN18 | 17/20 | 0.50 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964741 | 0.92 | EZH2 (0.51) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21156579 | 0.89 | EZH2 (0.48) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21157361 | 0.81 | EZH2 (0.63) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21113231 | 0.80 | EZH2 (0.80) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19964748 | 0.78 | EZH2 (0.69) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21157345 | 0.78 | EED (0.65) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21113052 | 0.77 | EED (0.51) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21113519 | 0.77 | EZH2 (0.67) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL28958935 | 0.76 | EED (0.52) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL21113310 | 0.76 | EED (0.68) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-B | Pyrido five-membered aromatic ring compound, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2022-11-15 | — | — | CN | disclosed |