Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 4/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.44 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.44 |
| ▸ | AEBP2 | Q6ZN18 | 4/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.30 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964637 | 0.82 | EED (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113071 | 0.79 | EED (0.50) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113329 | 0.74 | EED (0.80) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964642 | 0.70 | EED (0.69) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113072 | 0.68 | EED (0.37) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113310 | 0.67 | EED (0.68) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21240704 | 0.67 | EED (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21240649 | 0.66 | EZH2 (0.41) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113052 | 0.66 | EED (0.51) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113396 | 0.66 | EED (0.67) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-B | Pyrido five-membered aromatic ring compound, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2022-11-15 | — | — | CN | disclosed |