Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.61 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.48 |
| ▸ | WIZ | O95785 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984704 | 0.92 | CRBN (0.60) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL29986828 | 0.90 | CRBN (0.66) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL30985002 | 0.90 | CRBN (0.59) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL29986496 | 0.90 | CRBN (0.65) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL29986895 | 0.90 | CRBN (0.65) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL30984985 | 0.89 | CRBN (0.58) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL30985032 | 0.88 | CRBN (0.61) | CRBNIKZF2WIZESR1CSNK1A1 | |
| SCHEMBL30942272 | 0.88 | CRBN (0.54) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL27302673 | 0.88 | CRBN (0.54) | CRBNIKZF2WIZCSNK1A1 | |
| SCHEMBL27424010 | 0.88 | CRBN (0.56) | CRBNIKZF2WIZESR1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251224-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2022-12-01 | — | — | WO | disclosed |