Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815698 | 1.00 | HSD17B10 (0.61) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24815668 | 0.81 | HSD17B10 (0.64) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29986714 | 0.81 | HSD17B10 (0.64) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29987539 | 0.80 | HSD17B10 (0.55) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24814405 | 0.80 | HSD17B10 (0.55) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24815714 | 0.79 | POLB (0.55) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29986494 | 0.79 | POLB (0.55) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24814730 | 0.79 | HSD17B10 (0.54) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29987597 | 0.79 | HSD17B10 (0.54) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL26845899 | 0.79 | HSD17B10 (0.54) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |