Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | TEC | P42680 | 1/20 | 0.49 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386570 | 0.91 | TNK2 (0.54) | BTKEGFRTECTNK2CKS1B | |
| SCHEMBL16597764 | 0.91 | TNK2 (0.54) | BTKEGFRTECTNK2CKS1B | |
| SCHEMBL31379801 | 0.86 | TNK2 (0.63) | BTKEGFRTECTNK2 | |
| SCHEMBL31379800 | 0.86 | TNK2 (0.63) | BTKEGFRTECTNK2 | |
| SCHEMBL16597782 | 0.86 | TNK2 (0.63) | BTKEGFRTECTNK2 | |
| SCHEMBL22944329 | 0.82 | TNK2 (0.49) | BTKTNK2RORC | |
| SCHEMBL31386555 | 0.81 | BTK (0.53) | BTKEGFRTECTNK2CKS1B | |
| SCHEMBL16597682 | 0.81 | BTK (0.53) | BTKEGFRTECTNK2CKS1B | |
| SCHEMBL16598006 | 0.81 | BTK (0.71) | BTKEGFRTECTNK2 | |
| SCHEMBL16597588 | 0.80 | BTK (0.66) | BTKEGFRTECTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304606-B | Degradation agent for simultaneously targeting BTK and GSPT proteins | 清华大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-115304606-A | Degradation agent for simultaneously targeting BTK and GSPT1 proteins | 清华大学 | 2022-11-08 | — | — | CN | disclosed |