Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.65 |
| ▸ | GLP1R | P43220 | 2/20 | 0.59 |
| ▸ | GCGR | P47871 | 1/20 | 0.59 |
| ▸ | GIPR | P48546 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.56 |
| ▸ | NPY1R | P25929 | 3/20 | 0.56 |
| ▸ | NPY4R | P50391 | 3/20 | 0.56 |
| ▸ | VIPR2 | P41587 | 6/20 | 0.56 |
| ▸ | VIPR1 | P32241 | 4/20 | 0.55 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500564 | 1.00 | TFPI (0.65) | TFPIGLP1RGCGRGIPRNPY5R | |
| SCHEMBL30262126 | 0.88 | TFPI (0.62) | TFPIGLP1RGCGRGIPRNPY5R | |
| SCHEMBL29986817 | 0.88 | TFPI (0.52) | TFPIGLP1RGCGRGIPRVIPR2 | |
| SCHEMBL30037373 | 0.88 | TFPI (0.63) | TFPIGLP1RGCGRGIPRNPY5R | |
| SCHEMBL29794100 | 0.87 | TFPI (0.67) | TFPIGLP1RGCGRGIPRNPY5R | |
| SCHEMBL30037677 | 0.87 | TFPI (0.62) | TFPIGLP1RGCGRGIPRNPY5R | |
| SCHEMBL30038758 | 0.86 | VIPR1 (0.63) | TFPIGLP1RGCGRGIPRVIPR2 | |
| SCHEMBL29563482 | 0.85 | GLP1R (0.66) | TFPIGLP1RGCGRGIPRVIPR2 | |
| SCHEMBL31517010 | 0.85 | GLP1R (0.64) | TFPIGLP1RGCGRGIPRNPY5R | |
| SCHEMBL30480570 | 0.84 | VIPR1 (0.66) | TFPIGLP1RGCGRGIPRVIPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583892-B2 | Conus-based toxin peptides, nucleic acids encoding same and uses thereof in modulating NMDA receptors | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (IL) | 2026-03-24 | — | — | US | disclosed |
| US-11661440-B2 | Synthetic peptides that modulate the NMDA receptor | UNIVERSIDAD NACIONAL DE COLOMBIA (CO) | 2023-05-30 | — | — | US | disclosed |
| EP-4085066-A1 | CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS | Technion Research & Development Foundation Limited (IL) | 2022-11-09 | — | — | EP | disclosed |
| US-20220324922-A1 | CONUS-BASED TOXIN PEPTIDES, NUCLEIC ACIDS ENCODING SAME AND USES THEREOF IN MODULATING NMDA RECEPTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583892-B2 | Conus-based toxin peptides, nucleic acids encoding same and uses thereof in modulating NMDA receptors | GRIN1, GRIN3A, GRIN2B | TFPI 4266/4885GLP1R 324/4885GCGR 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.