SCHEMBL29988014

SCHEMBL29988014

CC1CNc2cc3ccccc3cc2N1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 5/20 0.37
CREBBP Q92793 5/20 0.37
EP300 Q09472 1/20 0.37
MEN1 O00255 2/20 0.36
GAA P10253 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
CASP1 P29466 1/20 0.36
MPI P34949 1/20 0.36
HTT P42858 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28519858 1.00 BRD4 (0.37) BRD4CREBBPEP300MEN1GAA
SCHEMBL30570961 0.79 BRD4 (0.50) BRD4CREBBPEP300MEN1GAA
SCHEMBL19225173 0.79 BRD4 (0.50) BRD4CREBBPEP300MEN1GAA
SCHEMBL2723593 0.79 BRD4 (0.50) BRD4CREBBPEP300MEN1GAA
SCHEMBL15508279 0.79 BRD4 (0.50) BRD4CREBBPEP300MEN1GAA
SCHEMBL29898376 0.79 BRD4 (0.50) BRD4CREBBPEP300MEN1GAA
SCHEMBL29004249 0.78 NPC1 (0.31) NPC1RAB9ACYP1A2CDK1MAPKAPK2
SCHEMBL16928520 0.78 NPC1 (0.31) NPC1RAB9ACYP1A2CDK1MAPKAPK2
SCHEMBL30570963 0.78 NPC1 (0.31) NPC1RAB9ACYP1A2CDK1MAPKAPK2
SCHEMBL29898372 0.78 NPC1 (0.31) NPC1RAB9ACYP1A2CDK1MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751170-A Method for directly preparing semi-hydrogenated nitrogen-containing aromatic heterocyclic compound from sugar 浙江大学 2023-09-15 CN disclosed
CN-111792999-B Dinaphthylamine compounds, and preparation method and application thereof 五邑大学 2022-08-09 CN disclosed