Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390257 | 0.92 | TLR2 (0.42) | MDM4TP53CASP3PIN1TLR2 | |
| SCHEMBL14403081 | 0.87 | MDM4 (0.42) | MDM4TP53CASP3PIN1MDM2 | |
| SCHEMBL13402610 | 0.87 | MDM4 (0.42) | MDM4TP53CASP3PIN1MDM2 | |
| SCHEMBL16325618 | 0.86 | MDM4 (0.42) | MDM4TP53CASP3MDM2 | |
| SCHEMBL29397738 | 0.86 | MDM4 (0.42) | MDM4TP53CASP3MDM2 | |
| SCHEMBL17117694 | 0.85 | MDM4 (0.41) | MDM4TP53CASP3PIN1TLR2 | |
| SCHEMBL17117698 | 0.84 | MDM4 (0.43) | MDM4TP53CASP3PIN1MDM2 | |
| SCHEMBL29401616 | 0.84 | MDM4 (0.43) | MDM4TP53CASP3MDM2 | |
| SCHEMBL29398493 | 0.84 | MDM4 (0.43) | MDM4TP53CASP3PIN1MDM2 | |
| SCHEMBL13402579 | 0.84 | MDM4 (0.43) | MDM4TP53CASP3PIN1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112175066-B | Method for preparing sertraline | 浙江苏泊尔制药有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-112175066-B | Method for preparing sertraline | 浙江苏泊尔制药有限公司 | 2022-12-02 | — | — | CN | disclosed |