Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 15/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20786668 | 1.00 | MAPK1 (0.50) | MAPK1MKNK1MKNK2ADORA2ACLK2 | |
| SCHEMBL20786566 | 0.92 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL22277866 | 0.91 | MAPK1 (0.49) | MAPK1ADORA2A | |
| SCHEMBL20786016 | 0.90 | MAPK1 (0.55) | MAPK1MKNK2CLK2DYRK1A | |
| SCHEMBL29988154 | 0.90 | MAPK1 (0.55) | MAPK1MKNK2CLK2DYRK1A | |
| SCHEMBL29989181 | 0.90 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL20786510 | 0.90 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL20786333 | 0.89 | MAPK1 (0.60) | MAPK1MKNK1MKNK2 | |
| SCHEMBL20786336 | 0.89 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL29988193 | 0.89 | MAPK1 (0.47) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032656-B | Heterocyclic compound kinase inhibitor and pharmaceutical composition and application thereof | 捷思英达医药技术（上海）有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-111032656-B | Heterocyclic compound kinase inhibitor and pharmaceutical composition and application thereof | 捷思英达医药技术（上海）有限公司 | 2022-12-02 | — | — | CN | disclosed |