SCHEMBL2999014

SCHEMBL2999014

CC(C)(CC1CCCc2ccccc21)C1CCCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.42
TBXAS1 P24557 1/20 0.42
IDO1 P14902 2/20 0.41
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19117311 0.83 IDO1 (0.44) IDO1SIGMAR1
SCHEMBL20706323 0.79 IDO1 (0.49) IDO1
SCHEMBL9515277 0.76 IDO1 (0.44) IDO1
SCHEMBL14815564 0.76 IDO1 (0.46) IDO1
SCHEMBL22808450 0.76 IDO1 (0.50) IDO1
SCHEMBL22721447 0.75 CYP19A1 (0.49) CYP19A1TBXAS1IDO1SIGMAR1
SCHEMBL30129841 0.75 CYP19A1 (0.49) CYP19A1TBXAS1IDO1SIGMAR1
SCHEMBL598590 0.75 CYP19A1 (0.49) CYP19A1TBXAS1IDO1SIGMAR1
SCHEMBL7898127 0.75 IDO1 (0.52) CYP19A1TBXAS1IDO1SIGMAR1
SCHEMBL24548535 0.74 MAPK1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0224259-B1 A WORKING FLUID FOR TRACTION DRIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-02-10 EP disclosed
US-4684754-A DECAHYDRONAPHTHALENE DERIVATIVES IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-08-04 US disclosed
EP-0224259-A2 A working fluid for traction drive IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-06-03 EP disclosed
US-4521324-A Fluid for traction drive IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-06-04 US disclosed