Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21070315 | 1.00 | CRBN (0.60) | CRBNDDB1KDM4EIKZF3 | |
| SCHEMBL21107340 | 0.87 | CRBN (0.65) | CRBNDDB1IKZF3 | |
| SCHEMBL22502706 | 0.85 | CRBN (0.60) | CRBNDDB1KDM4EIKZF3 | |
| SCHEMBL21069969 | 0.85 | CRBN (0.56) | CRBNDDB1KDM4EIKZF3 | |
| SCHEMBL21070381 | 0.85 | CRBN (0.67) | CRBNDDB1IKZF3 | |
| SCHEMBL32672139 | 0.84 | CRBN (0.58) | CRBNDDB1IKZF3 | |
| SCHEMBL26100228 | 0.84 | CRBN (0.58) | CRBNDDB1IKZF3 | |
| SCHEMBL21070715 | 0.84 | CRBN (0.66) | CRBNDDB1IKZF3 | |
| SCHEMBL31268329 | 0.83 | CRBN (0.51) | CRBNDDB1KDM4E | |
| SCHEMBL24764216 | 0.81 | CRBN (0.76) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |