Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAX | Q07812 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024339 | 1.00 | BAX (0.72) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL5024320 | 1.00 | BAX (0.72) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL29398838 | 1.00 | BAX (0.72) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL607745 | 1.00 | BAX (0.72) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL31038642 | 0.99 | MAPT (0.73) | BAXMAPTTP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL29462932 | 0.99 | MAPT (0.73) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL19419604 | 0.93 | BAX (0.63) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL5024368 | 0.84 | BAX (0.72) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL607771 | 0.84 | BAX (0.72) | BAXMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL609012 | 0.84 | BAX (1.00) | BAXMAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053454-B2 | Compositions for cryopreservation and methods of use thereof | EVERGREEN BIOSCIENCES (US) | 2024-08-06 | — | — | US | claimed |
| US-20240268372-A1 | Methods and Compositions for Extending Organ and Tissue Preservation | MASSACHUSETTS GEN HOSPITAL (US) | 2024-08-15 | — | — | US | disclosed |
| WO-2022241417-A1 | METHODS AND COMPOSITIONS FOR EXTENDING ORGAN AND TISSUE PRESERVATION | THE GENERAL HOSPITAL CORPORATION (US) | 2022-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053454-B2 | Compositions for cryopreservation and methods of use thereof | BAK1, BAX, BAD | BAX 2/4885MAPT 2314/4885TP53 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.