Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 12/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23647696 | 1.00 | CHUK (0.43) | CHUKLRRK2IKBKBMAPK1 | |
| SCHEMBL1017679 | 0.77 | CHUK (0.41) | CHUKMAPK1 | |
| SCHEMBL4012627 | 0.72 | CHUK (0.40) | CHUKLRRK2MAPK1 | |
| SCHEMBL29993346 | 0.71 | — | — | |
| SCHEMBL23647528 | 0.71 | — | — | |
| SCHEMBL19010829 | 0.69 | CHUK (0.71) | CHUKLRRK2IKBKB | |
| SCHEMBL31095312 | 0.69 | CHUK (0.71) | CHUKLRRK2IKBKB | |
| SCHEMBL1020911 | 0.69 | — | — | |
| SCHEMBL29993619 | 0.69 | — | — | |
| SCHEMBL29643720 | 0.67 | CHUK (0.41) | CHUKLRRK2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867720-B | Heteroaryl derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-116323622-A | Bicyclic heteroaryl derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022237178-A1 | BICYCLIC HETEROARYL DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-11-17 | — | — | WO | disclosed |
| CN-115340545-A | Bicyclic heteroaryl derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-11-15 | — | — | CN | disclosed |