Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22583692 | 1.00 | FGFR1 (0.72) | FGFR1HTTP4HB | |
| SCHEMBL1354830 | 0.88 | FGFR1 (0.71) | FGFR1HTT | |
| SCHEMBL29526516 | 0.88 | FGFR1 (0.71) | FGFR1HTT | |
| SCHEMBL29993159 | 0.86 | FGFR1 (0.74) | FGFR1HTT | |
| SCHEMBL20604030 | 0.86 | FGFR1 (0.74) | FGFR1HTT | |
| SCHEMBL22583615 | 0.84 | FGFR1 (0.63) | FGFR1HTT | |
| SCHEMBL29993895 | 0.84 | FGFR1 (0.63) | FGFR1HTT | |
| SCHEMBL7986426 | 0.84 | FGFR1 (1.00) | FGFR1HTT | |
| SCHEMBL3417304 | 0.84 | HTT (0.78) | FGFR1HTT | |
| SCHEMBL12822351 | 0.83 | FGFR1 (0.64) | FGFR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11465998-B2 | Therapeutic compounds and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465998-B2 | Therapeutic compounds and methods of use thereof | MYD88, C3AR1, FCGRT | FGFR1 4441/4885HTT 2914/4885P4HB 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.