Sugi Predict

Sugi Predict / Compounds / SCHEMBL29993325

SCHEMBL29993325

SCHEMBL29993325

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 7/20 0.65
▸ ECE1 P42892 6/20 0.63
▸ IL1RN P18510 7/20 0.61
▸ ERAP1 Q9NZ08 3/20 0.61
▸ ACE P12821 2/20 0.59
▸ CTSC P53634 1/20 0.59
▸ MMP2 P08253 1/20 0.57
▸ MMP9 P14780 1/20 0.57
▸ MMP8 P22894 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30099514 0.96 ERAP2 (0.68) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30052756 0.94 ECE1 (0.68) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30821831 0.94 ECE1 (0.68) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30051522 0.94 ERAP2 (0.72) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL31502300 0.94 ECE1 (0.68) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30931483 0.91 ERAP2 (0.66) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30051305 0.90 ACE (0.72) ERAP2ECE1ACECTSC
SCHEMBL31247322 0.89 ERAP2 (0.66) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL31388803 0.88 ERAP2 (0.72) ERAP2ECE1IL1RNERAP1ACE
Valyltryptophan SCHEMBL150532 0.88 ACE (0.75) ECE1ACECTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435143-B2 Caninized antibodies against canine CTLA-4 INTERVET INC. (US) 2025-10-07 — — US disclosed
US-20220251208-A1 Caninized Antibodies Against Canine CTLA-4 INTERVET INC. (US) 2022-08-11 — — US disclosed
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