SCHEMBL29993919

SCHEMBL29993919

N=C(N)NCCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.43
▸ NPY1R P25929 7/20 0.43
▸ NPY2R P49146 5/20 0.43
▸ NPY5R Q15761 5/20 0.43
▸ C5AR1 P21730 1/20 0.36
▸ KLK7 P49862 1/20 0.35
▸ ENPEP Q07075 3/20 0.35
▸ GLP1R P43220 1/20 0.35
▸ SCTR P47872 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31453827 0.94 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL38660264 0.94 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL31399748 0.94 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL31453796 0.93 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL30291866 0.93 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RKLK7
SCHEMBL30866245 0.93 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL30905088 0.93 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RKLK7
SCHEMBL31088231 0.93 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL29736425 0.93 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL4957131 0.92 NPY4R (0.43) NPY4RNPY1RNPY2RNPY5RC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11471490-B2 T cells surface-loaded with immunostimulatory fusion molecules and uses thereof TORQUE THERAPEUTICS, INC. (US) 2022-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11471490-B2 T cells surface-loaded with immunostimulatory fusion molecules and uses thereof CD4, ICOS, IL2 NPY4R 2533/4885NPY1R 2316/4885NPY2R 2319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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