Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.67 |
| ▸ | SMO | Q99835 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936802 | 1.00 | IGF1R (0.67) | IGF1RSMOCTSSTAS2R8 | |
| SCHEMBL2936799 | 1.00 | IGF1R (0.67) | IGF1RSMOCTSSTAS2R8 | |
| Trifluoroacetic Acid SCHEMBL3736464 | 0.94 | IGF1R (0.61) | IGF1RSMOCTSSTAS2R8 | |
| Trifluoroacetic Acid SCHEMBL3732089 | 0.94 | IGF1R (0.61) | IGF1RSMOCTSSTAS2R8 | |
| Trifluoroacetic Acid SCHEMBL2937627 | 0.94 | IGF1R (0.61) | IGF1RSMOCTSSTAS2R8 | |
| SCHEMBL2938454 | 0.90 | IGF1R (0.55) | IGF1RCTSS | |
| SCHEMBL2938450 | 0.90 | IGF1R (0.55) | IGF1RCTSS | |
| SCHEMBL2936828 | 0.90 | IGF1R (0.58) | IGF1RSMOCTSS | |
| SCHEMBL2939398 | 0.90 | IGF1R (0.67) | IGF1RSMOCTSSTAS2R8 | |
| SCHEMBL2932195 | 0.90 | IGF1R (0.67) | IGF1RSMOCTSSTAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |