Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704157 | 1.00 | KCNH2 (0.42) | KCNH2DRD2HTR2AHTR2CMAP2K7 | |
| SCHEMBL23704163 | 0.85 | TLR9 (0.40) | DRD2HTR2AMAP2K7TLR9TLR8 | |
| SCHEMBL29994372 | 0.85 | TLR9 (0.40) | DRD2HTR2AMAP2K7TLR9TLR8 | |
| SCHEMBL28864911 | 0.80 | PROKR1 (0.44) | KCNH2DRD2HTR2AHTR2CPROKR1 | |
| SCHEMBL29994010 | 0.77 | GAA (0.35) | HTR2AHTR2CMAP2K7PRMT5PARP1 | |
| SCHEMBL23704265 | 0.77 | GAA (0.35) | HTR2AHTR2CMAP2K7PRMT5PARP1 | |
| Hydrochloric Acid SCHEMBL23704353 | 0.76 | GAA (0.36) | HTR2AHTR2CMAP2K7PRMT5PARP1 | |
| Hydrochloric Acid SCHEMBL29994246 | 0.76 | GAA (0.36) | HTR2AHTR2CMAP2K7PRMT5PARP1 | |
| SCHEMBL23707284 | 0.74 | PROKR1 (0.41) | PROKR1PARP1 | |
| SCHEMBL9269516 | 0.70 | KDM4E (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052860-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4097084-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-115052860-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2022-09-13 | — | — | CN | disclosed |