SCHEMBL29994103

C[C@@H](O)[C@H](NC(=O)CN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.52

▸	VIPR2	P41587	5/20	0.50

▸	VIPR1	P32241	2/20	0.50

▸	IL23R	Q5VWK5	3/20	0.49

▸	KEAP1	Q14145	1/20	0.49

▸	NPY2R	P49146	2/20	0.48

▸	GHSR	Q92847	2/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30463288	0.90	SLC15A2 (0.48)	TFPINPY2R
SCHEMBL17176533	0.89	TFPI (0.62)	TFPIIL23RNPY2RGHSR
SCHEMBL29689104	0.88	TFPI (0.52)	TFPIVIPR1IL23R
SCHEMBL30414039	0.88	NPY4R (0.57)	TFPIVIPR2VIPR1NPY2RGHSR
SCHEMBL30413575	0.88	IL23R (0.62)	TFPIIL23R
SCHEMBL30974259	0.87	TFPI (0.53)	TFPIVIPR1IL23RKEAP1
SCHEMBL30182811	0.87	TFPI (0.63)	TFPIVIPR2VIPR1KEAP1
SCHEMBL31085370	0.87	NPY4R (0.50)	NPY2R
SCHEMBL30701868	0.86	OPRL1 (0.54)	TFPIVIPR2VIPR1IL23RKEAP1
SCHEMBL30701872	0.86	OPRL1 (0.54)	TFPIVIPR2VIPR1IL23RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12435143-B2	Caninized antibodies against canine CTLA-4	INTERVET INC. (US)	2025-10-07	—	—	US	disclosed
US-20220251208-A1	Caninized Antibodies Against Canine CTLA-4	INTERVET INC. (US)	2022-08-11	—	—	US	disclosed