SCHEMBL29995277

SCHEMBL29995277

CSCC(=O)Nc1ccc(NC(=O)c2cc(NC(=O)[C@H]3[C@H](c4ccc(F)c(C(F)(F)F)c4)C3(Cl)Cl)ccc2Cl)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.37
KMT2A Q03164 6/20 0.37
LMNA P02545 4/20 0.37
ALDH1A1 P00352 1/20 0.35
RECQL P46063 1/20 0.35
GRM4 Q14833 2/20 0.35
MAPT P10636 5/20 0.35
MAPK1 P28482 1/20 0.35
TP53 P04637 1/20 0.35
IDO1 P14902 1/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HDAC3 O15379 1/20 0.34
EGFR P00533 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21449936 1.00 MEN1 (0.37) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL21449937 0.93 MEN1 (0.36) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL21450003 0.92 MEN1 (0.35) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18147042 0.88 MEN1 (0.45) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18147038 0.88 MEN1 (0.45) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL21449944 0.86 MEN1 (0.40) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL29995395 0.86 MEN1 (0.40) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL21450001 0.86 MEN1 (0.40) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL20901062 0.86 MEN1 (0.40) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL20050803 0.86 KMT2A (0.41) MEN1KMT2ALMNAALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111698906-B Molecules having pesticidal utility, compositions and pest control methods related thereto 美国陶氏益农公司 2022-10-18 CN disclosed