Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.65 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075561 | 0.83 | HIF1A (0.56) | HIF1AEPAS1TSHRTP53SMN1; SMN2 | |
| SCHEMBL23673967 | 0.80 | HIF1A (0.72) | HIF1AEPAS1TSHRCYP3A4 | |
| SCHEMBL4293719 | 0.80 | HIF1A (1.00) | HIF1AEPAS1KMT2AHCAR2LMNA | |
| SCHEMBL23673934 | 0.78 | TSHR (0.56) | HIF1AEPAS1TSHRPOLBKMT2A | |
| SCHEMBL14829020 | 0.77 | HIF1A (0.72) | HIF1AEPAS1TSHRPOLBKMT2A | |
| SCHEMBL23673936 | 0.76 | HIF1A (0.64) | HIF1AEPAS1SMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL23673944 | 0.75 | HIF1A (0.70) | HIF1AEPAS1CYP3A4 | |
| SCHEMBL4299480 | 0.74 | HIF1A (1.00) | HIF1AEPAS1TP53SMN1; SMN2 | |
| SCHEMBL13576938 | 0.72 | HIF1A (1.00) | HIF1AEPAS1POLB | |
| SCHEMBL23673940 | 0.71 | HIF1A (0.70) | HIF1AEPAS1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4098647-A1 | DISUBSTITUTED ADAMANTYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR SUPPRESSING CANCER GROWTH COMPRISING SAME AS ACTIVE INGREDIENT | Onecuregen Co., Ltd. (KR) | 2022-12-07 | — | — | EP | disclosed |