Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK13 | Q9HB14 | 8/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26921174 | 1.00 | KCNK13 (0.52) | KCNK13CYP11B2RPS6KA5TLR7TSHR | |
| SCHEMBL29995644 | 0.90 | KCNK13 (0.61) | KCNK13CYP11B2TLR7TSHRALDH1A1 | |
| SCHEMBL26921332 | 0.90 | KCNK13 (0.61) | KCNK13CYP11B2TLR7TSHRALDH1A1 | |
| SCHEMBL29995832 | 0.84 | KCNK13 (0.53) | KCNK13CYP11B2RPS6KA5TSHRALDH1A1 | |
| SCHEMBL26921448 | 0.84 | KCNK13 (0.53) | KCNK13CYP11B2RPS6KA5TSHRALDH1A1 | |
| SCHEMBL29995176 | 0.81 | KCNK13 (0.61) | KCNK13TSHRALDH1A1HTTMAPT | |
| SCHEMBL26923493 | 0.81 | KCNK13 (0.61) | KCNK13TSHRALDH1A1HTTMAPT | |
| SCHEMBL26921418 | 0.78 | KCNK13 (0.79) | KCNK13TSHRALDH1A1HTTMAPT | |
| SCHEMBL29995693 | 0.78 | KCNK13 (0.79) | KCNK13TSHRALDH1A1HTTMAPT | |
| SCHEMBL29995356 | 0.78 | KCNK13 (0.53) | KCNK13TLR7GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | claimed |
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |