Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | KCNK13 | Q9HB14 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | PRKACA | P17612 | 3/20 | 0.63 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.63 |
| ▸ | GSK3B | P49841 | 3/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.63 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922470 | 1.00 | TSHR (0.78) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL29995749 | 0.88 | KCNK13 (0.76) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL26922395 | 0.88 | KCNK13 (0.76) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL29995731 | 0.88 | TSHR (0.78) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL26921748 | 0.88 | TSHR (0.78) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL15225165 | 0.88 | TSHR (1.00) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL26921036 | 0.87 | KCNK13 (1.00) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL29995147 | 0.87 | KCNK13 (1.00) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL29995836 | 0.86 | KCNK13 (0.77) | TSHRMAPTHTTALDH1A1LMNA | |
| SCHEMBL26921131 | 0.86 | KCNK13 (0.77) | TSHRMAPTHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | claimed |
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-116981665-A | Novel compounds | 思瑞万斯公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |