Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 17/20 | 0.53 |
| ▸ | BCL2 | P10415 | 5/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744703 | 1.00 | MCL1 (0.53) | MCL1BCL2BCL2L1 | |
| SCHEMBL24745227 | 0.92 | MCL1 (0.53) | MCL1BCL2BCL2L1 | |
| SCHEMBL24744742 | 0.88 | MCL1 (0.51) | MCL1BCL2BCL2L1 | |
| SCHEMBL24773778 | 0.88 | MCL1 (0.53) | MCL1BCL2BCL2L1 | |
| SCHEMBL24745225 | 0.87 | MCL1 (0.55) | MCL1BCL2BCL2L1 | |
| SCHEMBL24744716 | 0.82 | MCL1 (0.53) | MCL1BCL2BCL2L1 | |
| SCHEMBL24773792 | 0.82 | MCL1 (0.62) | MCL1BCL2BCL2L1 | |
| SCHEMBL24744727 | 0.81 | MCL1 (0.52) | MCL1BCL2BCL2L1 | |
| SCHEMBL24745300 | 0.81 | MCL1 (0.63) | MCL1BCL2BCL2L1 | |
| SCHEMBL24744665 | 0.81 | MCL1 (0.67) | MCL1BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255888-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |