Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 19/20 | 0.67 |
| ▸ | BCL2 | P10415 | 3/20 | 0.67 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24745150 | 1.00 | MCL1 (0.67) | MCL1BCL2BCL2L1ALB | |
| Hydrochloric Acid SCHEMBL30000917 | 0.99 | MCL1 (0.66) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL24772885 | 0.93 | MCL1 (0.68) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL30000826 | 0.92 | MCL1 (0.62) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL24745151 | 0.92 | MCL1 (0.62) | MCL1BCL2BCL2L1ALB | |
| Hydrochloric Acid SCHEMBL29262142 | 0.92 | MCL1 (0.61) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL24745319 | 0.91 | MCL1 (0.61) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL30001335 | 0.91 | MCL1 (0.61) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL24745261 | 0.90 | MCL1 (0.71) | MCL1BCL2BCL2L1 | |
| SCHEMBL24745210 | 0.89 | MCL1 (0.59) | MCL1BCL2BCL2L1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255888-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |