Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.89 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arbortristoside C SCHEMBL422794 | 0.82 | ELANE (0.62) | ELANEHSP90AA1STAT3MEN1MAPT | |
| SCHEMBL420506 | 0.82 | ELANE (0.62) | ELANEHSP90AA1STAT3MEN1MAPT | |
| SCHEMBL30561993 | 0.82 | HSP90AA1 (0.62) | ELANEHSP90AA1POLBMAPTSMN1; SMN2 | |
| SCHEMBL29896779 | 0.80 | ELANE (0.65) | ELANEPOLBCTDSP1STAT3MEN1 | |
| SCHEMBL20572206 | 0.80 | ELANE (0.65) | ELANEPOLBCTDSP1STAT3MEN1 | |
| SCHEMBL29425927 | 0.80 | ELANE (0.65) | ELANEPOLBCTDSP1STAT3MEN1 | |
| SCHEMBL29425898 | 0.80 | ELANE (0.65) | ELANEPOLBCTDSP1STAT3MEN1 | |
| Luzonoside D SCHEMBL422895 | 0.76 | STAT3 (0.55) | ELANESTAT3MEN1MAPTKMT2A | |
| Luzonoside C SCHEMBL421025 | 0.76 | STAT3 (0.55) | ELANESTAT3MEN1MAPTKMT2A | |
| SCHEMBL31179906 | 0.76 | ELANE (0.60) | ELANEPOLBCTDSP1STAT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114886907-A | (E) Application of-6-O-p-coumaroyl paederosidic methyl ester in preparation of medicine for preventing/treating liver injury | 山东中医药大学附属医院 | 2022-08-12 | — | — | CN | claimed |
| CN-114886907-A | (E) Application of-6-O-p-coumaroyl paederosidic methyl ester in preparation of medicine for preventing/treating liver injury | 山东中医药大学附属医院 | 2022-08-12 | — | — | CN | disclosed |
| CN-114886907-A | (E) Application of-6-O-p-coumaroyl paederosidic methyl ester in preparation of medicine for preventing/treating liver injury | 山东中医药大学附属医院 | 2022-08-12 | — | — | CN | disclosed |