Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.57 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24752230 | 1.00 | LRRK2 (0.57) | LRRK2MAP4K1MAPK3PTK2ALK | |
| SCHEMBL24752236 | 0.94 | LRRK2 (0.56) | LRRK2MAP4K1MAPK3PTK2 | |
| SCHEMBL24752702 | 0.93 | LRRK2 (0.55) | LRRK2MAP4K1MAPK3PTK2 | |
| SCHEMBL24752266 | 0.92 | LRRK2 (0.59) | LRRK2MAP4K1MAPK3PTK2ALK | |
| SCHEMBL30002260 | 0.92 | LRRK2 (0.59) | LRRK2MAP4K1MAPK3PTK2ALK | |
| SCHEMBL24752708 | 0.91 | LRRK2 (0.55) | LRRK2MAP4K1MAPK3PTK2ALK | |
| SCHEMBL24752232 | 0.91 | LRRK2 (0.55) | LRRK2MAP4K1MAPK3PTK2ALK | |
| SCHEMBL29137444 | 0.91 | LRRK2 (0.56) | LRRK2MAP4K1MAPK3PTK2EGFR | |
| SCHEMBL24752243 | 0.90 | LRRK2 (0.62) | LRRK2MAP4K1MAPK3PTK2ALK | |
| SCHEMBL30001781 | 0.90 | LRRK2 (0.62) | LRRK2MAP4K1MAPK3PTK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253081-A1 | PHOSPHINE OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 希格生科（深圳）有限公司 | 2022-12-08 | — | — | WO | disclosed |