SCHEMBL30002336

SCHEMBL30002336

CCOc1cc(C(CC(=O)NO)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC

nearest known ligand 0.84

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 17/20 0.84
PDE4C Q08493 17/20 0.84
PDE4A P27815 11/20 0.84
PDE4D Q08499 11/20 0.84
HTR2B P41595 1/20 0.76
TNF P01375 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13337346 1.00 PDE4B (0.84) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL7848491 1.00 PDE4B (0.84) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL476946 1.00 PDE4B (0.84) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL537033 0.93 PDE4B (0.90) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL537699 0.93 PDE4B (0.90) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL537255 0.93 PDE4B (0.90) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL23392623 0.91 PDE4B (0.87) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL21494501 0.91 PDE4B (0.87) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL21494457 0.91 PDE4B (0.87) PDE4BPDE4CPDE4APDE4DHTR2B
SCHEMBL3131846 0.91 PDE4B (0.87) PDE4BPDE4CPDE4APDE4DHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220324991-A1 BCMA-BINDING ANTIBODIES AND USES THEREOF CELGENE CORPORATION 2022-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324991-A1 BCMA-BINDING ANTIBODIES AND USES THEREOF CD79B, BCL6, CD22 PDE4B 4638/4885PDE4C 4515/4885PDE4A 4566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.