Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909101 | 1.00 | KRAS (0.46) | KRAS | |
| SCHEMBL28909114 | 0.92 | KRAS (0.43) | KRAS | |
| SCHEMBL30411909 | 0.92 | KRAS (0.43) | KRAS | |
| SCHEMBL28909006 | 0.89 | KRAS (0.48) | KRAS | |
| SCHEMBL30002196 | 0.89 | KRAS (0.48) | KRAS | |
| SCHEMBL28678845 | 0.86 | KRAS (0.52) | KRAS | |
| SCHEMBL30001905 | 0.86 | KRAS (0.52) | KRAS | |
| SCHEMBL28692060 | 0.86 | KRAS (0.41) | KRAS | |
| SCHEMBL29572849 | 0.85 | KRAS (0.43) | KRAS | |
| SCHEMBL25829666 | 0.85 | KRAS (0.43) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199170-A1 | TETRACYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 浙江海正药业股份有限公司 | 2022-09-29 | — | — | WO | disclosed |