Aminoquinol

Aminoquinol

SCHEMBL30002729

CCN(CC)CCCC(C)Nc1cc(/C=C/c2ccccc2Cl)nc2cc(Cl)ccc12

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 3/20 0.59
CYP2D6 P10635 3/20 0.59
CHRM2 P08172 3/20 0.59
CHRM4 P08173 3/20 0.59
CHRM5 P08912 3/20 0.59
ADRA2A P08913 3/20 0.59
CHRM1 P11229 3/20 0.59
ADRA2B P18089 3/20 0.59
ADRA2C P18825 3/20 0.59
CHRM3 P20309 3/20 0.59
KCNH2 Q12809 3/20 0.59
PRNP P04156 2/20 0.59
MTOR P42345 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
CYP2C19 P33261 2/20 0.59
TMEM97 Q5BJF2 2/20 0.59
SIGMAR1 Q99720 2/20 0.59
ACE2 Q9BYF1 2/20 0.59
APP P05067 1/20 0.59
NQO2 P16083 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminoquinol SCHEMBL1612756 1.00 CXCR4 (0.59) CXCR4CYP2D6CHRM2CHRM4CHRM5
Aminoquinol SCHEMBL1612755 1.00 CXCR4 (0.59) CXCR4CYP2D6CHRM2CHRM4CHRM5
Aminoquinol SCHEMBL29462347 1.00 CXCR4 (0.59) CXCR4CYP2D6CHRM2CHRM4CHRM5
Aminoquinol SCHEMBL706642 0.95 HSD17B10 (0.62) CXCR4CYP2D6CHRM2CHRM4CHRM5
Aminoquinol SCHEMBL706641 0.95 HSD17B10 (0.62) CXCR4CYP2D6CHRM2CHRM4CHRM5
Aminoquinol SCHEMBL29578527 0.95 HSD17B10 (0.62) CXCR4CYP2D6CHRM2CHRM4CHRM5
SCHEMBL7828401 0.95 CXCR4 (0.51) CXCR4CYP2D6CHRM2CHRM4CHRM5
SCHEMBL12713542 0.92 CHRM2 (0.58) CXCR4CYP2D6CHRM2CHRM4CHRM5
SCHEMBL16142475 0.91 CHRM2 (0.57) CXCR4CYP2D6CHRM2CHRM4CHRM5
SCHEMBL7820026 0.91 CHRM2 (0.57) CXCR4CYP2D6CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347645-A1 NEURO-MESENCHYME UNITS CONTROL ILC2 AND OBESITY VIA A BRAIN-ADIPOSE CIRCUIT Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud Foundation (PT) 2024-04-10 EP claimed
WO-2022254255-A1 NEURO-MESENCHYME UNITS CONTROL ILC2 AND OBESITY VIA A BRAIN-ADIPOSE CIRCUIT FUNDACAO D. ANNA DE SOMMERCHAMPALIMAUD E DR. (PT) 2022-12-08 WO claimed
EP-4347645-A1 NEURO-MESENCHYME UNITS CONTROL ILC2 AND OBESITY VIA A BRAIN-ADIPOSE CIRCUIT Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud Foundation (PT) 2024-04-10 EP disclosed
WO-2022254255-A1 NEURO-MESENCHYME UNITS CONTROL ILC2 AND OBESITY VIA A BRAIN-ADIPOSE CIRCUIT FUNDACAO D. ANNA DE SOMMERCHAMPALIMAUD E DR. (PT) 2022-12-08 WO disclosed