SCHEMBL30003450

SCHEMBL30003450

CC(C)OC(=O)Oc1c2ccccc2c(OC(=O)OC(C)C)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
IDO1 P14902 1/20 0.40
GAA P10253 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20398675 1.00 TSHR (0.43) TSHRPDCD1CD274CA12CA1
SCHEMBL20398613 0.90 KDM4E (0.43) TSHRPDCD1CD274CA12CA1
SCHEMBL31080863 0.90 KDM4E (0.43) TSHRPDCD1CD274CA12CA1
SCHEMBL9654685 0.89 KDM4E (0.50) TSHRPDCD1CD274CA12CA1
SCHEMBL23271668 0.88 KDM4E (0.42) TSHRPDCD1CD274KDM4EHSD17B10
SCHEMBL30002558 0.88 KDM4E (0.42) TSHRPDCD1CD274KDM4EHSD17B10
SCHEMBL20398665 0.87 KDM4E (0.41) TSHRPDCD1CD274KDM4EHSD17B10
SCHEMBL31080914 0.87 TSHR (0.41) TSHRPDCD1CD274CA12CA1
SCHEMBL20398662 0.87 TSHR (0.41) TSHRPDCD1CD274CA12CA1
SCHEMBL30003198 0.87 KDM4E (0.41) TSHRPDCD1CD274KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454090-B Compounds having a polycyclic aromatic skeleton and endoperoxide compounds thereof 川崎化成工业株式会社 2024-08-23 CN disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed