Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658335 | 1.00 | PPARA (0.55) | PPARAPPARGPPARDS1PR3HSD17B10 | |
| SCHEMBL24742416 | 0.94 | PPARA (0.50) | PPARAPPARGPPARDHSD17B10MAPT | |
| SCHEMBL30004652 | 0.94 | PPARA (0.50) | PPARAPPARGPPARDHSD17B10MAPT | |
| SCHEMBL24658330 | 0.93 | PPARG (0.48) | PPARAPPARGPPARDS1PR3MAPT | |
| SCHEMBL30003514 | 0.93 | PPARG (0.48) | PPARAPPARGPPARDS1PR3MAPT | |
| SCHEMBL12732396 | 0.92 | PPARG (0.57) | PPARAPPARGPPARDS1PR3HSD17B10 | |
| SCHEMBL2466112 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDHSD17B10MAPT | |
| SCHEMBL24658541 | 0.90 | PPARA (0.51) | PPARAPPARGPPARDS1PR3HSD17B10 | |
| SCHEMBL30003656 | 0.90 | PPARA (0.51) | PPARAPPARGPPARDS1PR3HSD17B10 | |
| SCHEMBL1765936 | 0.90 | PPARD (0.68) | PPARAPPARGPPARDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333379-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2025-10-30 | — | — | US | disclosed |
| US-12297168-B2 | Compounds useful for treating liver diseases | ABIONYX PHARMA SA (FR) | 2025-05-13 | — | — | US | disclosed |
| US-20240199575-A1 | COMPOUNDS USEFUL FOR TREATING LIVER DISEASES | ABIONYX PHARMA SA (FR) | 2024-06-20 | — | — | US | disclosed |
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2023-09-07 | — | — | US | disclosed |
| US-11634387-B2 | Compounds useful for treating liver diseases | ABIONYX PHARMA SA (FR) | 2023-04-25 | — | — | US | disclosed |
| US-20220363632-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | PPARA 94/4885PPARG 71/4885PPARD 332/4885 |
| US-20240199575-A1 | COMPOUNDS USEFUL FOR TREATING LIVER DISEASES | SLC10A1, FABP1, CPT1A | PPARA 94/4885PPARG 71/4885PPARD 332/4885 |
| US-11634387-B2 | Compounds useful for treating liver diseases | SLC10A1, FABP1, CPT1A | PPARA 94/4885PPARG 71/4885PPARD 332/4885 |
| US-20250333379-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | PPARA 94/4885PPARG 71/4885PPARD 332/4885 |
| US-12297168-B2 | Compounds useful for treating liver diseases | SLC10A1, FABP1, CPT1A | PPARA 94/4885PPARG 71/4885PPARD 332/4885 |
| US-20220363632-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | PPARA 94/4885PPARG 71/4885PPARD 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.