Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452517 | 1.00 | CYP2A6 (0.52) | CYP2A6CYP1A2AGXTTDP1KMT2A | |
| SCHEMBL184681 | 0.91 | CYP1A2 (0.39) | CYP2A6CYP1A2AGXTTDP1KMT2A | |
| SCHEMBL185504 | 0.91 | NQO1 (0.39) | CYP2A6CYP1A2AGXTTDP1KMT2A | |
| SCHEMBL6056041 | 0.86 | NQO1 (0.37) | CYP2A6CYP1A2AGXTTDP1KMT2A | |
| SCHEMBL5788899 | 0.82 | CYP2A6 (0.52) | CYP2A6CYP1A2AGXTTDP1KMT2A | |
| SCHEMBL17042486 | 0.81 | CYP2A6 (0.57) | CYP2A6CYP1A2KMT2AMEN1KDM4E | |
| SCHEMBL23607927 | 0.80 | CYP2A6 (0.56) | CYP2A6CYP1A2KMT2AMEN1KDM4E | |
| SCHEMBL11708368 | 0.79 | ESR1 (0.49) | CYP1A2TDP1KMT2AMEN1MAPT | |
| SCHEMBL11711900 | 0.78 | CYP3A4 (0.48) | CYP1A2TDP1KMT2AMEN1MAPT | |
| SCHEMBL17042459 | 0.78 | CYP2A6 (0.54) | CYP2A6CYP1A2TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698582-A1 | CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS | Wacker Chemie AG (DE) | 2026-02-25 | — | — | EP | disclosed |
| WO-2025085745-A1 | MODULATORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2024217692-A1 | CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS | WACKER CHEMIE AG (DE) | 2024-10-24 | — | — | WO | disclosed |
| EP-4347702-A1 | CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS | Wacker Chemie AG (DE) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022253413-A1 | CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS | WACKER CHEMIE AG (DE) | 2022-12-08 | — | — | WO | disclosed |