Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.86 |
| ▸ | DYRK1A | Q13627 | 20/20 | 0.86 |
| ▸ | WNT1 | P04628 | 15/20 | 0.86 |
| ▸ | CLK2 | P49760 | 2/20 | 0.63 |
| ▸ | CLK3 | P49761 | 2/20 | 0.63 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.63 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.63 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.63 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.63 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19516118 | 1.00 | GSK3B (0.86) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19516137 | 1.00 | GSK3B (0.86) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19516119 | 1.00 | GSK3B (0.86) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30005595 | 1.00 | GSK3B (0.86) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515672 | 0.93 | GSK3B (0.83) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30005417 | 0.93 | GSK3B (1.00) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19516166 | 0.93 | GSK3B (1.00) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515940 | 0.86 | GSK3B (0.75) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515499 | 0.86 | DYRK1A (0.78) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515543 | 0.86 | DYRK1A (0.75) | GSK3BDYRK1AWNT1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | claimed |