Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 1.00 |
| ▸ | GSK3B | P49841 | 19/20 | 1.00 |
| ▸ | WNT1 | P04628 | 15/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19515943 | 1.00 | DYRK1A (1.00) | DYRK1AGSK3BWNT1 | |
| SCHEMBL30005223 | 0.92 | GSK3B (1.00) | DYRK1AGSK3BWNT1 | |
| SCHEMBL19515527 | 0.92 | GSK3B (1.00) | DYRK1AGSK3BWNT1 | |
| SCHEMBL24219753 | 0.91 | GSK3B (0.98) | DYRK1AGSK3BWNT1 | |
| SCHEMBL19516263 | 0.90 | GSK3B (1.00) | DYRK1AGSK3BWNT1 | |
| SCHEMBL30004539 | 0.90 | GSK3B (1.00) | DYRK1AGSK3BWNT1 | |
| SCHEMBL23741628 | 0.89 | GSK3B (0.82) | DYRK1AGSK3BWNT1 | |
| SCHEMBL23740981 | 0.89 | DYRK1A (0.80) | DYRK1AGSK3BWNT1 | |
| SCHEMBL24219633 | 0.89 | DYRK1A (0.79) | DYRK1AGSK3BWNT1 | |
| SCHEMBL19515227 | 0.88 | DYRK1A (0.84) | DYRK1AGSK3BWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | disclosed |