Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.79 |
| ▸ | GSK3B | P49841 | 6/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.64 |
| ▸ | WNT1 | P04628 | 3/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544273 | 1.00 | ABL1 (0.79) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL19516245 | 1.00 | ABL1 (0.79) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL19516243 | 1.00 | ABL1 (0.79) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL20946112 | 0.94 | ABL1 (0.89) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL30425762 | 0.94 | ABL1 (0.89) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL20946020 | 0.90 | ABL1 (0.70) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL20946022 | 0.90 | ABL1 (0.70) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL9938850 | 0.88 | ABL1 (1.00) | ABL1 | |
| SCHEMBL19516307 | 0.86 | ABL1 (0.76) | ABL1GSK3BDYRK1AWNT1JAK2 | |
| SCHEMBL30005555 | 0.86 | ABL1 (0.76) | ABL1GSK3BDYRK1AWNT1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | disclosed |