Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 1.00 |
| ▸ | GSK3B | P49841 | 18/20 | 0.76 |
| ▸ | WNT1 | P04628 | 9/20 | 0.64 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | CLK3 | P49761 | 2/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19515378 | 1.00 | DYRK1A (1.00) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL23740909 | 0.90 | DYRK1A (0.81) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL20946633 | 0.87 | DYRK1A (0.77) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL20947004 | 0.87 | DYRK1A (0.77) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL30005095 | 0.86 | DYRK1A (1.00) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL19515228 | 0.86 | DYRK1A (1.00) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL20950693 | 0.86 | DYRK1A (0.76) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL20951198 | 0.85 | DYRK1A (0.75) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL19516272 | 0.85 | DYRK1A (0.73) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL30004798 | 0.85 | DYRK1A (0.73) | DYRK1AGSK3BWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | disclosed |