Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 19/20 | 0.70 |
| ▸ | WNT1 | P04628 | 9/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | CLK3 | P49761 | 1/20 | 0.58 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19516186 | 1.00 | GSK3B (0.70) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19516187 | 1.00 | GSK3B (0.70) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19516327 | 0.90 | GSK3B (0.67) | GSK3BDYRK1AWNT1USP30 | |
| SCHEMBL19516204 | 0.90 | GSK3B (0.70) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515815 | 0.88 | GSK3B (0.73) | GSK3BDYRK1AWNT1USP30 | |
| SCHEMBL30004923 | 0.85 | GSK3B (0.69) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515255 | 0.85 | GSK3B (0.69) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515254 | 0.85 | GSK3B (0.69) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19515749 | 0.83 | GSK3B (0.69) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19544165 | 0.83 | GSK3B (0.67) | GSK3BDYRK1AWNT1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | claimed |