Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624377 | 1.00 | TOP2A (0.31) | TOP2ATOP2BPOLB | |
| SCHEMBL21624378 | 1.00 | TOP2A (0.31) | TOP2ATOP2BPOLB | |
| SCHEMBL21624330 | 0.84 | AR (0.30) | — | |
| SCHEMBL30668473 | 0.84 | AR (0.30) | — | |
| SCHEMBL21624331 | 0.84 | AR (0.30) | — | |
| SCHEMBL21636853 | 0.84 | AR (0.30) | — | |
| SCHEMBL30006267 | 0.83 | TOP2A (0.30) | TOP2ATOP2B | |
| SCHEMBL21636891 | 0.83 | TOP2A (0.30) | TOP2ATOP2B | |
| SCHEMBL21624190 | 0.80 | — | — | |
| SCHEMBL21624192 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771046-B | Other substituted triazoloquinoxaline derivatives | 格吕伦塔尔有限公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |