Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987177 | 1.00 | PARP1 (0.53) | PARP1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL17064514 | 0.85 | PARP1 (0.43) | PARP1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL6584943 | 0.85 | PARP1 (0.50) | PARP1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL28242748 | 0.83 | TDP1 (0.52) | TSHRTDP1L3MBTL1UNGTP53 | |
| Urea SCHEMBL29001189 | 0.83 | TDP1 (0.52) | PARP1TSHRTDP1POLBUNG | |
| SCHEMBL723945 | 0.82 | UNG (0.68) | PARP1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL15036 | 0.82 | UNG (0.68) | TSHRTDP1HSD17B10UNGTP53 | |
| SCHEMBL21777904 | 0.82 | UNG (0.68) | TSHRTDP1HSD17B10UNGTP53 | |
| SCHEMBL29373775 | 0.82 | UNG (0.68) | TSHRTDP1HSD17B10UNGTP53 | |
| SCHEMBL2164103 | 0.82 | UNG (0.47) | TSHRTDP1POLBL3MBTL1UNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |