Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 19/20 | 0.95 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.95 |
| ▸ | CDK7 | P50613 | 11/20 | 0.95 |
| ▸ | CCNH | P51946 | 11/20 | 0.95 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.95 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.95 |
| ▸ | CDK2 | P24941 | 10/20 | 0.95 |
| ▸ | CDK9 | P50750 | 10/20 | 0.95 |
| ▸ | MNAT1 | P51948 | 10/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948470 | 1.00 | CCNK (0.95) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL28948465 | 1.00 | CCNK (0.95) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL25605311 | 0.97 | CCNK (1.00) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL29492550 | 0.97 | CCNK (1.00) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL21184348 | 0.91 | CCNK (0.85) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL24840739 | 0.91 | CCNK (1.00) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL24839879 | 0.87 | CCNK (1.00) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL30204078 | 0.87 | CCNK (1.00) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL30260874 | 0.86 | CCNK (0.94) | CCNKCDK12CDK7CCNHCCNT1 | |
| SCHEMBL24839876 | 0.86 | CCNK (1.00) | CCNKCDK12CDK7CCNHCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040998-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-23 | — | — | WO | disclosed |
| CN-114907407-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 江苏先声药业有限公司 | 2022-08-16 | — | — | CN | disclosed |