Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005781 | 0.84 | KMT2A (0.46) | KMT2A | |
| SCHEMBL18126613 | 0.73 | KCNH2 (0.44) | MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL25254954 | 0.73 | MAPT (0.44) | MEN1KMT2ACYP19A1 | |
| SCHEMBL18112910 | 0.71 | OXER1 (0.49) | MEN1KMT2AOXER1 | |
| P-Xylene SCHEMBL20836571 | 0.71 | HTR2A (0.56) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL2356590 | 0.69 | HTR2A (0.60) | ATMTDP1L3MBTL1 | |
| SCHEMBL11686076 | 0.68 | KMT2A (0.68) | MEN1KMT2AATMTDP1L3MBTL1 | |
| SCHEMBL4672103 | 0.68 | OXER1 (0.52) | KMT2AOXER1 | |
| SCHEMBL3016081 | 0.68 | TAAR1 (0.61) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL31500446 | 0.68 | TAAR1 (0.61) | MEN1KMT2ANOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559974-B | Seven-membered ring fused cyclopenta [ b ] indole derivative and synthesis method and application thereof | 华东师范大学 | 2022-10-25 | — | — | CN | disclosed |